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Department of Laboratory Medicine, Asahikawa Medical University

お問い合わせTEL.0166-68-2745

〒078-8510 旭川市緑が丘東2条1丁目1-1

研 究

主な研究テーマ

◆動脈硬化の分子機構の解明と新たな検査法の開発
◆血栓性疾患の発生機構の研究
◆パラダイムシフトから質的変化を標的とした新しい検査方法を探る

研究業績

  • Yoshie Kawahara, Kohei Ohtsuka, Kimine Tanaka, Mayumi Yamanaka, Hiroyuki Kamiya, Takayuki Kunisawa, Satoshi Fuji. Use of laboratory testing for prediction of postoperative bleeding volume in cardiovascular surgery. Thrombosis Journal 2021.10 publishued.
  • J. Takahashi, T. Sato, N. Kobayashi, M. Sado, M. S. Aung, N. Kobayashi, S. Fujii
    Bacteroides pyogenes isolated from appendiceal abscess in a patient without animal contact.
    New Microbe and New Infect 2021:44
  • Yu Ota, Kenji Takahashi, Shin Otake, Yosui Tamaki, Mitsuyoshi Okada, Irene Yan, Kazunobu Aso, Satoshi Fujii, Tushar Patel, Masakazu Haneda. Extracellular RNA transfer from non-malignant human cholangiocytes can promote cholangiocarcinoma growth. Febs Open Bio doil;10.1002/2211-5463.13294
  • Naoki Watanabe, Takatoshi Yonezawa, Takako Yanagiya, Daisuke Hanada, Masatoshi Sado. Satoshi Fujii. Evaluation of the potential impact of NAAT for Clostridioides difficile on antimicrobial treatment. The Journal of Japanese Sosiety of Laboratory Medicine 2021; 69: 410-414.
  • Tomonori Sugiura, Yasuaki Dohi, Hiroyuki Takase, Satoshi Fujii, Yoshihiro Seo, Nobuyuki Ohte. Analytical evaluation of serum non-transferrin bound iron and the relationships with oxidative stress and cardiac load in the general population. Medicine 2021; 100: 7
  • Motoshi Suzuki, Ke Cao, Seiichi Kato, Naoki Mizutani, Kouji Tanaka, Chinatsu Arima, Mei Chee Tai, Norie Nakatani, Kiyoshi Yanagisawa, Toshiyuki Takeuchi, Hanxiao Shi, Yasuyoshi Mizutani, Atsuko Niimi, Tetsuo Taniguchi, Takayuki Fukui, Kohei Yokoi, Keiko Wakahara, Yoshinori Hasegawa, Yukiko Mizutani, Soichiro Iwaki, Satoshi Fujii, Akira Satou, Keiko Tamiya-Koizumi, Takashi Murate, Mamoru Kyogashima, Shuta Tomida , Takashi Takahashi.CERS6 required for cell migration and metastasis in lung cancer. J Cell Mol Med 2020; 24:11949-11959.
  • Tomonori Sugiura, Yasuaki Dohi, Hiroyuki Takase, Satoshi Fujii, MD, Yoshihiro Seo, Nobuyuki Ohte. Relationship of pulmonary function with myocardial microdamage and oxidative stress in the Japanese population without a history of cardiopulmonary disease. Medicine 2020; 99: 35(e21945)
  • Satoshi Fujii, Kazumi Akasaka, Kenji Takahashi. Low levels of circulating extracellular vesicle-encapsulated HULC are associated with left ventricular hypertrophy in Japanese. Research and Practice in Thrombosis and Haemostasis 2020; 4S1: 1005-1006
  • Hayato Ise, Hiroto Kitahara, Kyohei Oyama, Keiya Takahashi, Hirotsugu Kanda, Satoshi Fujii, Takayuki Kunisawa, Hiroyuki Kamiya. Hypothermic circulatory arrest induced coagulopathy: rotational thromboelastometry analysis. General Thoracic and Cardiovascular Surgery 2020; 68:754-761
  • Kenji Takahashi, Kazuya Koyama1, Yu Ota, Hidetaka Iwamoto, Keisuke Yamakita, Satoshi Fujii, Yohei Kitano. The Interaction Between Long Non-coding RNA HULC and MicroRNA-622 via Transfer by Extracellular Vesicles Regulates Cell Invasion and Migration in Human Pancreatic CancerFrontiers in Oncology published: 23 June 2020 doi: 10.3389/fonc.2020.01013
  • Ito K, Ito E , Saito K, Tomoda Y, Akasaka K, Fujii S. Measurements of brachial artery cross-sectional vascular area and volume elastic modulus using automated oscillometric measurements: reproducibility between examinersand intra-rater reliability. Rinsho Byori 2020; 68: 383-389
  • Tatsuya Mizoguchi, Tomonori Sugiura, Yasuaki Dohi, Hiroyuki Takase, Satoshi Fujii, Yoshihiro Seo, Nobuyuki Ohte. Indices of left ventricular voltage on electrocardiogram are closely associated with serum cardiac troponin I levels in normotensive Japanese individuals. Medicine 2020; 99: 19 (e19992)
  • Kenji Takahashi1, Yu Ota, Takayuki Kogure, Yuko Suzuki, Hidetaka Iwamoto, Keisuke Yamakita, Yohei Kitano, Satoshi Fujii, Masakazu Haneda, Tushar Patel, Tsuguhito Ota. Circulating Extracellular Vesicle-encapsulated HULC is a Potential Biomarker for Human Pancreatic Cancer. Cancer Science 2020; 111:98-111.
  • Tomonori Sugiura, Yasuaki Dohi, Hiroyuki Takase, Sumiyo Yamashita, Tetsuya Mizoguchi, Satoshi Fujii, Nobuyuki Ohte. Close association between circulating high-sensitivity cardiac troponin I and metabolic syndrome in the general population. Hypertention Research. Hypertens Res. 2019; 42: 1768-1775
  • Ando K, Fujiya M, Nomura Y, Inaba Y, Sugiyama Y, Kobayashi Y, Iwama T, Ijiri M, Takahashi K, Ueno N, Kashima S, Moriichi K, Tanabe H, Mizukami Y, Akasaka K, Fujii S, Yamada S, Nakase H, Okumura T. The Incidence and Risk Factors of Venous Thromboembolism in Patients with Inflammatory Bowel Disease: A Prospective Multicenter Cohort Study. Digestion 2019; 100: 220-237
  • Ito A, Niizeki N, Sado M, Akasaka K, Fujii S. Association of high-sensitivity cardiac troponin, fibroblast growth factor 23 and left ventricular hypertrophy in Japanese patients with reduced renal function. Hokkaido J Med Sci 2019; 94: 13-20
  • Y. Kawahara ; K. Ohtsuka ; K. Tanaka ; M. Yamanaka ; S. Fujii. Dynamic Coagulability during Cardiovascular Surgery and its Correlations with Bleeding Volume. Res Pract Thromb Hemost 2019; 3 (Suppl. 1): 462
  • Murasawa Y, Furuta K, Noda Y, Nakamura H, Fujii S, Isogai Z. Ointment bases regulate the wound-healing process by modifying the hyaluronan-rich matrices. Wound Repair and Regeneration 2018; 26: 437-445.
  • Sugiura T, Dohi Y, Takase H, Fujii S, Ohte N. Findings relevant to the QRS wave in the resting electrocardiogram are associated with circulating concentrations of high-sensitivity cardiac troponin I in the general population. J Am Soc Hypertens. 2018;12(8):614-620.
  • Ota Y, Takahashi K, Otake S, Tamaki Y, Okada M, Aso K, Makino Y, Fujii S, Ota T, Haneda M. Extracellular vesicle-encapsulated miR-30e suppresses cholangiocarcinoma cell invasion and migration via inhibiting epithelial-mesenchymal transition. Oncotarget. 2018;9(23):16400-16417.
  • Sugiura T, Dohi Y, Takase H, Ito A, Fujii S, Ohte N. Differential effects of brachial and central blood pressures on circulating levels of high-sensitivity cardiac troponin I in the general population.Atherosclerosis. 2018;269:185-191.
  • Saito T, Kawamura Y, Sato N, Sugiyama E, Okada M, Takeuchi T, Akasaka K, Hasebe N. Cerebral Microbleeds Remain for Nine Years: A Prospective Study with Yearly Magnetic Resonance Imaging. J Stroke Cerebrovasc Dis. 2018;27(2):315-320.
  • Yonezawa T, Watari T, Ashizawa K, Hanada D, Yanagiya T, Watanabe N, Terada T, Tomoda Y, Fujii S. Development of an improved rapid BACproR protocol and a method for direct identification from blood-culture-positive bottles using matrix-assisted laser desorption ionization time-of-flight mass spectrometry.J Microbiol Methods. 2018; 148: 138-144.
  • Murasawa Y, Nakamura H, Watanabe K, Kanoh H, Koyama E, Fujii S, Kimata K, Zako M, Yoneda M, Isogai Z. The Versican G1 Fragment and Serum-Derived Hyaluronan-Associated Proteins Interact and Form a Complex in Granulation Tissue of Pressure Ulcers. Am J Pathol. 2018; 188: 432-449.
  • Sanagawa A, Ogasawara M, Kusahara Y, Yasumoto M, Iwaki S, Fujii S. Investigation into Differences in Level of Knowledge about Hypertension between High School Students and Elderly People. Yakugaku Zasshi. 2017;137(6):783-789.
  • Sugiura T, Dohi Y, Takase H, Yamashita S, Fujii S, Ohte N. Oxidative Stress is Closely Associated with Increased Arterial Stiffness, Especially in Aged Male Smokers without Previous Cardiovascular Events: A Cross-Sectional Study. J Atheroscler Thromb. 2017.7
  • Yoshinaga K, Tamaki N, Fujii S. Molecular Determinants of Functional Changes and Fibrosis Determined by Novel Automated Oscillometric Approach to Measure Brachial Artery Vascular Volume Elastic Modulus in Chronic Kidney Disease. 2017.03.19 ACC Washington DC, USA
  • Ahmed Talib, Nobuyuki Satoh, Marina Imahashi, Kumiko Saitou, Eisuke Ito, Eitaro Sugiyama, Naka Sakamoto, Kazumi Akasaka, Yuichiro Kwaamura, Naoyuki Hasebe. Analysis of 12-lead based T-wave alterans in rsik stratification of J-wave syndrome. 2017.03.17 Japanese Circulation Society Kanazawa, Japan
  • Keiichiro Yoshinaga, Yoichi M. Ito , Satoshi Fujii, Saori Nishio, Noriki Ochi, Chietsugu Katoh, Mamiko Inoue, Mutumi Nishida, Osamu Manabe, Nagara Tamaki. Molecular Determinants of Functional Changes and Fibrosis Determined by Novel Automated Oscillometric Approach to Measure Brachial Artery Vascular Volume Elastic Modulus 2017.03.18 Japanese Circulation Society Kanazawa, Japan.
  • Kitahara H, Takeda T, Akasaka K, Kamiya H. Bow Hunter syndrome elicited by vertebral arterial occlusion after total arch replacement. Interact Cardiovasc Thorac Surg. 2017;24(5):806-808.
  • Maruyama K, Nakagawa N, Saito E, Matsuki M, Takehara N, Akasaka K, Sato N, Hasebe N. Malnutrition, renal dysfunction and left ventricular hypertrophy synergistically increase the long-term incidence of cardiovascular events. Hypertens Res. 2016;39(9):633-9.
  • Talib AK, Sato N, Myojo T, Sugiyama E, Nakagawa N, Sakamoto N, Tanabe Y, Fujino T, Takeuchi T, Akasaka K, Matsuhashi H, Saijo Y, Kawamura Y, Doi A, Hasebe N. Insight into specific pro-arrhythmic triggers in Brugada and early repolarization syndromes: results of long-term follow-up. Heart Vessels. 2016;31(12):2035-2044.
  • Satoshi Fujii, Tomonori Sugiura, Yasuaki Dohi, Nobuyuki Ohte. MicroRNA in atherothromobosis: is it useful as a disease marker? Thrombosis Journal 2016; 14 (Suppl 1) 21; 141-143
  • Masami Ijiri, Mikihiro Fujiya, Nobuhiro Ueno, Shin Kashima, Tomohisa Watari, Satoshi Fujii, Toshikatu Okumura. Syphilis infection throughout the whole gastrointestinal tract. Endoscopy. 2016; 48(S01):E338-E339.
  • Fujii S. Bleeding Tendency in Asian-Pacific Area. Cardiovascular Seminar TH.CVS272, November 15, 2016. American Heart Association Scientific Sessions. New Orleans, USA
  • Satoshi Fujii, Atsushi Itoh, Yumi Watanabe. Biomarkers for Cardiovascular Diseases: Their Clinical
    Significances and Future Directions. Annals of Nuclear Cardiology 2016; 2(1): 94-98.
  • Noriki Ochi, Keiichiro Yoshinaga, Yoichi M. Ito, Yuuki Tomiyama, Mamiko Inoue, Mutsumi Nishida, Osamu Manabe, Hitoshi Shibuya, Chikara Shimizu, Eriko Suzuki, Satoshi Fujii, Chietsugu Katoh, Nagara Tamaki. Comprehensive Assessment of Impaired Peripheral and Coronary Artery Endothelial Function in Smokers Using Brachial Artery Ultrasound and Oxygen-15-labeled Water PET Journal of Cardiology 2016; 68: 316-323.
  • Maruyama K, Nakagawa N, Saito E, Matsuki M, Takehara N, Akasaka K, Sato N, Hasebe N. Malnutrition, renal dysfunction and left ventricular hypertrophy synergistically increase the long-term incidence of cardiovascular events. Hypertens Res. 2016 May 12. [Epub ahead of print]
  • Sakamoto N, Sato N, Talib AK, Sugiyama E, Minoshima A, Tanabe Y, Fujino T, Takeuchi T, Akasaka K, Saijo Y, Kawamura Y, Hasebe N. Late Gadolinium Enhancement on Cardiac MRI Correlates with QT Dynamicity Represented by QT/RR Relationship in Patients with Ventricular. Ann Noninvasive Electrocardiol 2016; 21(2): 126-135.
  • Suzuki M, Cao K, Kato S, Komizu Y, Mizutani N, Tanaka K, Arima C, Tai MC, Yanagisawa K, Togawa N, Shiraishi T, Usami N, Taniguchi T, Fukui T, Yokoi K, Wakahara K, Hasegawa Y, Mizutani Y, Igarashi Y, Inokuchi JI, Iwaki S, Fujii S, Satou A, Matsumoto Y, Ueoka R, Tamiya-Koizumi K, Murate T, Nakamura M, Kyogashima M, Takahashi T. Targeting CERS6-dependent Metastasis-prone Phenotype in Lung Cancer Cells. J Clin Invest J Clin Invest. 2016; 126: 254-265
  • Akimasa Sanagawa, Soichiro Iwaki, Moyoko Asai, Daisuke Sakakibara, Hiroaki Norimoto, Burton E Sobel, Satoshi Fujii. Sphingosine 1 phosphate induced by hypoxia increases the expression of PAI 1 in HepG2 cells via HIF 1α. Molecular Medicine Reports 2016; 14: 1841-1848.
  • Keiichiro Yoshinaga, Satoshi Fujii, Yuuki Tomiyama. Anatomical and Functional Estimations of Brachial Artery Diameter and Elasticity Using Oscillometric Measurements with a Quantitative Approach. Pulse 2016; 4(1): 1-10.
  • Sugiura T, Yamashita S, Hirowatari Y, Fujii S, Ohte N. Serotonin in Peripheral Blood Reflects Oxidative Stress and Plays a Crucial Role in Atherosclerosis: Novel Insights toward Holistic Anti-atherothrombotic Strategy Atherosclerosis 2016;246:157-160
  • Sakamoto N, Sato N, Talib AK, Sugiyama E, Minoshima A, Tanabe Y, Fujino T, Takeuchi T, Akasaka K, Saijo Y, Kawamura Y, Hasebe N. Late Gadolinium Enhancement on Cardiac MRI Correlates with QT Dynamicity Represented by QT/RR Relationship in Patients with Ventricular Arrhythmias.Ann Noninvasive Electrocardiol. 2016;21(2):126-35.
  • Daisuke Hanada, Yoshie Kawahara, Ohtsuka Kouhei, Hiroyuki Takahashi, Yutaka Tomoda, Satoshi Fujii. The first report of the reference ranges of rotational thromboelastometry (ROTEM) in Japanese. The 32nd World Congress of Biomedical Laboratory Science, Kobe 2016.9.3-4
  • Junya Takahashi, Noriyasu Niizeki, Hitomi Kurose, Keisuke Nozawa, Naomi Onodera, Mineji Tachibana, Yutaka Tomoda, Satoshi Fujii Evalution of Immunobiochemical Hybrid-type Automatic Analyzer cobas8000. The 32nd World Congress of Biomedical Laboratory Science, Kobe 2016.9.3-4
  • Nobuyuki Sato, Rie Sasaki, Marina Imahashi, Eisuke Ito, Kumiko Saito, Haruyo Kubota, Ahmed Karim Talib, Naka Sakamoto, Kazumi Akasaka, Yasuaki Saijo, Yuichiro Kawamura, Satoshi Fujii, Naoyuki Hasebe. The relationship between repolarization parameters and serum electrolyte levels in patients with J wave syndromes. Magnesium Research 2015; 28: 1-13.
  • Sakamoto N, Sato N, Oikawa K, Karim Talib A, Sugiyama E, Minoshima A, Tanabe Y, Takeuchi T, Akasaka K, Saijo Y, Kawamura Y, Hasebe N. Late gadolinium enhancement of cardiac magnetic resonance imaging indicates abnormalities of time-domain T-wave alternans in hypertrophic cardiomyopathy with ventricular tachycardia. Heart Rhythm. 2015;12:1747-55
  • Nobuyuki Sato, Rie Sasaki, Marina Imahashi, Eisuke Ito, Kumiko Saito, Haruyo Kubota, Ahmed Karim Talib, Naka Sakamoto, Kazumi Akasaka, Yasuaki Saijo, Yuichiro Kawamura, Satoshi Fujii, Naoyuki Hasebe. The relationship between repolarization parameters and serum electrolyte levels in patients with J wave syndromes. Magnesium Research 2015; 28: 1-13.
  • Keisuke Nozawa, Noriyasu Niizeki, Fumiyori Saito, Atsushi Ito, Yoshie Kawahara, Hiroyuki Takahashi, Yutaka Tomoda, Satoshi Fujii. Hyperglucosuria with SGLT2 inhibitors falsely lowers parameters of specific gravity and leukocytes on urine test-strip reactions. The 32nd World Congress of Biomedical Laboratory Science, Kobe 2016.9.3-4
  • Ito A, Niizeki N, Tomoda Y, Akasaka K, Fujii S. Renal function is the major influencing factor for the high-sensitivity cardiac troponin measurements. The 32nd World Congress of Biomedical Laboratory Science, Kobe 2016.9.3-4.
  • Masashi Satoh, Miyuki Hoshino, Koki Fujita, Misao Iizuka, Satoshi Fujii, Christopher S. Clingan, Luc Van Kaer, Kazuya Iwabuchi. Adipocyte-specific CD1d-deficiency mitigates diet-induced obesity and insulin resistance in mice. Scientific Reports 2016; 6.
  • Fujii S, Ito S. TNF-α Production in Natural Killer T Cell Hybridoma and Mouse NKT cells is Regulated by Sphingosine-1-Phosphate. International Atherosclerosis Newsletter, Commentary on the IAS website. (IAS website only)
  • Yuuki Tomiyama, Keiichiro Yoshinaga, Satoshi Fujii, Noriki Ochi, Mamiko Inoue, Mutumi Nishida, Kumi Aziki, Hideo Nishibayashi, Tatsunori Horie, Chietsugu Katoh, Nagara Tamaki. Accurate quantitative measurements of brachial artery cross-sectional vascular area and vascular volume elastic modulus using automated oscillometric measurements - comparison with brachial artery ultrasound. Hypertens Res 2015; 38: 478-484
  • Shimada R, Dohi Y, Kimura K, Fujii S. Development of the Japanese medication adherence scale and verification of its reliability and validity in hypertensive patients. Pharmacology and Pharmacy 2015; 6: 118-124
  • Sugiura T, Dohi Y, Yamashita S, Iwaki S, Ito S, Sanagawa A, Ohte N, Fujii S. Circulating level of microRNA-126 may be a potential biomarker for recovery from smoking-related vascular damage in middle-aged habitual smokers. Int J Cardiol: Heart and Vasculature 2015; 7: 83-87.
  • Satoh H, Fujii S, Tsutsui H. Persistent depression is a significant risk factor for the deevelopment of arteriosclerosis in middle-aged Japanese male subjects. Hypertens Res 2015; 38: 84-88.
  • Sakamoto N, Sato N, Goto M, Kobayashi M, Takehara N, Takeuchi T, Talib AK, Sugiyama E, Minoshima A, Tanabe Y, Akasaka K, Kawabe J, Kawamura Y, Doi A, Hasebe N. Three cases of corticosteroid therapy triggering ventricular fibrillation in J-wave syndromes. Heart Vessels. 2014;29:867-72
  • Talib AK, Sato N, Kawabata N, Sugiyama E, Sakamoto N, Tanabe Y, Fujino T, Takeuchi T, Saijo Y, Akasaka K, Kawamura Y, Hasebe N. Repolarization characteristics in early repolarization and brugada syndromes: insight into an overlapping mechanism of lethal arrhythmias. J Cardiovasc Electrophysiol. 2014;25:1376-84.
  • Yoshinaga K, Ohira H, Tsujino I, Katoh C, Kasai K, Manabe O, Sato T, Oyama-Manabe N, Fujii S, Ito Y, Nishimura M, Tamaki N. Elevated right ventricular oxidative metabolism evaluated using C-11 acetate PET in patients with pulmonary hypertension. European Journal of Nuclear Medicine and Molecular Imaging 2014; 41:1240-50.
  • Ito S, Iwaki S, Kondo R, Satoh M, Iwabuchi K, Ohkawa R, Mishima Y, Yatomi Y, Furumoto T, Tsutsui H, Fujii S. TNF-α production in NKT cell hybridoma is regulated by sphingosine-1-phosphate: implications for inflammation in atherosclerosis. Coronary Artery Disease 2014; 25:311-20.
  • BURTON ELIAS SOBEL (1937-2013): His Friends Speak. American Journal of Cardiology 2014; 113: 402-405
  • Fuji S. Resolution of left atrial thrombus with novel oral anticoagulants. J Cardiol Cases 2014; 10: 241-242 (Editorial)
  • Ito S, Iwaki S, Kondo R, Satoh M, Iwabuchi K, Ohkawa R, Mishima Y, Yatomi Y, Furumoto T, Tsutsui H, Fujii S. TNF-α production in NKT cell hybridoma is regulated by sphingosine-1-phosphate: implications for inflammation in atherosclerosis. Coron Artery Dis. 2014; 25(4): 311-20.
  • Andoh Y, Ogura H, Satoh M, Shimano K, Okuno H, Fujii S, Ishimori N, Eshima K, Otani T, Nakai Y, Van Kaer L, Tsutsui H, Onoe K, Iwabuchi K. Natural killer T cells are required for lipopolysaccharide-mediated enhancement of atherosclerosis in apolipoprotein E-deficient mice. Immunobiology 2013; 218: 561-569.
  • Satoh H, Fujii S, Tsutsui H. The Relation between habitual sleep duration and blood pressure values in Japanese male subjects. Environment Health and Preventive Medicine 2013; 18: 215-220.
  • Sugiura1 T, Dohi Y, Hirowatari Y, Yamashita S, Ohte N, Kimura G, Fujii S. Cigarette Smoking Induces Vascular Damage and Persistent Elevation of Plasma Serotonin Unresponsive to 8 Weeks of Smoking Cessation. Int J Cardiol 2013; 166: 748-749.
  • Mizutani N, Kobayashi M, Sobue S, Ichihara M, Ito H, Tanaka K, Iwaki S, Fujii S, M.D. Ito Y, Tamiya-Koizumi K, Takagi A, Kojima T, Naoe T, Suzuki M, Nakamura M, Banno Y, Nozawa Y, Murate T. Sphingosine kinase 1 expression is downregulated during differentiation of Friend cells due to decreased c-MYB. Biochimica et Biophysica Acta - Molecular Cell Research 2013; 1833: 1006-1016.
  • Noda Y, Saito M, Watanabe K, Sanagawa A, Sobajima Y, Fujii S. Physicochemical characterization of tretinoin tocoferil emulsion and povidone-iodine sugar ointment blend developed for improved regulation of wound moisture. Chem Pharm Bull 2013; 61: 700-705
  • Itoh S, Yokoyama R, Kamoshida G, Okada H, Takii T, Tsuji T, Fujii S, Onozaki K. Staphylococcal superantigen-like protein 10 (SSL10) inhibits blood coagulation by binding to prothrombin and factor Xa via their γ-carboxyglutamic acid (Gla) domain J Biol Chem 2013; 288: 21569-21580
  • Fujii S. Insulin Resistance and Heart Failure: Underlying Molecular Mechanisms and Potential Pharmacological Solutions. J Cardiovasc Pharmacol 2013; 62: 379-380.
  • Ito S, Iwaki S, Koike K, Yuda Y, Nagasaki A, Ohkawa R, Yatomi Y, Furumoto T, Tsutsui H, Sobel B, Fujii S. Increased plasma sphingosine-1-phosphate in obese subjects and its capacity to increase expression of plasminogen activator inhibitor-1 in adipocytes. Coronary Artery Disease 2013; 24: 642-650.
  • Kazumi Akasaka, Erika Saito, Takaya Higuchi, et al. Aortic regurgitation caused by fibrous strand rupture in a fenestrated aortic valve. J Echocardiogr 2012; 10: 151-153.
  • Talib A, Nakagawa N, Akasaka K,et.al. The balance of fetuin-A and osteoprotegerin is independently associated with diastolic dysfunction in hemodialysis patients. Hypertens Res 2012; 35(4): 426-433.
  • Matuki M, Sato N, Akasaka K, et al. Brugada syndrome whose ST-segment changes were enhanced by antihistamines and antiallergenic drugs. Intern Med 2009; 48:1009-1013.
  • Tashiro N, Sato N, Akasaka K, et al. Brugada syndrome Ccase: Difficult differentiation between a concealed from and tricyclic antidepressant-induced brugada sign. Intern Med 2009; 48:1535-1539.
  • Takahashi F, Hasebe N, Akasaka K, et al. Hyperinsulinemia is an independent predictor for complex atherosclerotic lesion of thoractic aorta in non-diabetic patients. Atherosclerosis 2006; 187:336-342.
  • Akasaka K, Akasaka N, Di Luozzo G, et al: Homocysteine promotes p38-dependent chemotaxis in bovine aortic smooth muscle cells. J Vasc Surg 2005; 41(3): 517-522.
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  • 及川貴允、高橋裕之、渡辺愉美、伊藤敦巳、辻 真紀、佐渡正敏、藤井 聡. IgG非分泌を伴うベンスジョーンズ型形質細胞性白血病. 第92回北海道医学検査学会.2018.10.20-21,苫小牧
  • 赤坂和美. 特別講演「動脈硬化診療の様々な場面で頸動脈エコーを役立てる」動脈硬化疾患up to date勉強会.2018.5.12,福島県郡山市
  • 藤井 聡、生田克哉、奥山峰志、新関紀康、高橋裕之、河原好絵 貯血に伴う Hb 低下を迅速に予測する新規臨床検査法の開発と応用 自己血輸血 2016. 29. 157-164.
  • 赤坂和美、河端奈穂子、藤井 聡.日本臨床検査医学会北海道支部総会50回記念ミニシンポジウム「臨床検査の最近の話題」超音波検査環境に関するアンケート調査報告 第50回日本臨床検査医学会北海道支部総会・第26回日本臨床検査医学会北海道支部例会.旭川 2016.11.5
  • 田中希実音、大塚浩平、河原好絵、高橋裕之、花田大輔、渡辺直樹、友田 豊、藤井 聡. 当院におけるクリオプレシピテート使用状況の調査 輸血細胞治療学会北海道地方会.2016.11.26 札幌.
  • 河原好絵、大塚浩平、花田大輔、大原律子、友田 豊、藤井 . シンポジウム「自己血輸血における有害事象当院における輸血副作用の実態調査 30回日本自己血輸血学会学術総会.2017. 3. 11 横浜.
  • 赤坂和美、河端奈穂子、藤井 聡.臨床検査医のライフワークバランスと当院での支援体制 第63回日本臨床検査医学会学術集会ワークショップ「新専門医時代〜臨床検査医学がアピールできること〜」2016.09.03 神戸
  • 赤坂和美.パネルディスカッション:超音波検査環境に関する工夫・アイデア 女性の視点から・男性の視点から循環器領域における現状と課題.日本超音波医学会第89回学術集会 2016年5月27-29日,京都
  • 赤坂和美、工藤正俊、飯島尋子、上原麻理子、斎藤明子、椎名 毅、高野真澄、谷口信行、畠 二郎、平井都始子、古川まどか、山口 匡.パネルディスカッション:日本超音波医病学会が取り組むキャリア支援 日本超音波医学会男女共同参画委員会 アンケート調査報告.日本超音波医学会第89回学術集会 2016年5月27-29日,京都
  • 斉藤史頼、伊藤栄祐、河部里穂、西中麻里奈、笹木理恵、斉藤久美子、佐渡正敏、赤坂和美、藤井 聡、入江 徹. 第91回学会奨励賞「正中神経の感覚神経伝導検査におけるピットフォール〜腋窩部尺骨神経刺激でみられた波形成分についての考察〜 北臨技会誌 2018;16(2): 88-92
  • 渡辺直樹、柳谷貴子、花田大輔、佐渡正敏、藤井 聡.EXTRAGEN ZRを用いたTRCReadyの結核菌群およびMAC検出性能の評価.医学検査 2019; 68(2): 296-301
  • 橘 峰司.臨床検査における国立大学病院の存在意義.全国国立大学臨床検査技師会会誌 2016; 36: 4-5.
  • 藤井 聡. 支部研究室だより 臨床検査医学講座、臨床検査・輸血部の紹介. 臨床化学 2016; 45: 288-289.

  • 新関 紀康、黒瀬 瞳、伊藤 敦己、橘 峰司、友田 豊、藤井 聡 ラテックス シスタチンCキット「ヤマサ」の基礎的検討 医学と薬学 2015; 72: 499-504
  • 藤井 聡 動脈硬化性疾患と慢性炎症、血栓症:臨床検査の視点から 臨床病理 2015; 63: 605-611
  • 新関紀康、黒瀬瞳、伊藤敦巳、高橋順也、斉藤史頼、小野寺直美、橘峰司、友田豊、藤井聡、森山隆則 LAP測定試薬との異常反応を呈した原発性マクログロブリン血症のM蛋白の解析 電気泳動 2015; 59:39-44
  • 友田 豊.免疫血清検査 クロスマッチ 臨床検査 2015; 59(11)増刊号: 1252-1255
  • 友田 豊.輸血過誤、輸血副作用時の対応 臨床検査 2015; 59(11)増刊号: 1259
  • 渡 智久.自動分析装置を用いた微生物の同定と現場での応用.MEDICAL TECHNOLOGY 2015; 42(7): 718-728.
  • 東 由桂、渡 智久、柴崎有紀、米沢太亨、山内紫織、友田 豊、藤井 聡.血液培養から分離されたAcinetobacter 属菌の同定に関する検討.日本臨床微生物学雑誌 2015; 25: 213-222.
  • 伊藤敦巳、新関紀康、黒瀬 瞳、米沢太亨、笹木理恵、橘 峰司、友田 豊、紀野修一、藤井 聡 ラテックス凝集反応による4種のTP抗体測定試薬の基本性能の評価と判定不一致検体の精査 臨床病理 2015; 63: 25-31.
  • 赤坂和美、長谷部直幸. IV.臓器障害・合併症評価の検査 特殊検査 超音波検査・MRI・CT 日本臨牀 2014; 72: 149-152
  • 藤井 聡 miRNA (マイクロRNA, microRNA) 臨床高血圧学 別冊 日本臨床 2014; 72:218-221 日本臨床(東京)
  • 監修:三神大世 編集:湯田 聡,山田 聡,赤坂和美.エコーでコラボ主治医と検査者の相互理解を深める心エコー奥義. 医学書院 2014年3月発行.
  • 紀野修一.患者中心の輸血医療(PBM.医学のあゆみ 2014; 249(5): 487.
  • 紀野修一.患者中心の輸血医療(PBM)における臨床検査技師の役割.MEDICAL TECHNOLOGY 2014; 42(12): 1250-1253.

旭川医科大学臨床検査医学講座旭川医科大学臨床検査医学講座

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臨床検査・輸血部
旭川医科大学
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